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The existence of driver alterations is affiliated with quick progression. Even though a number of alterations are enriched in CLL when compared to MBL, both equally phases share an identical driver composition. (
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mutations, in whom rituximab seems to own very little additional value.59 Other genomic subgroups, including sufferers with BIRC3
mutations and complicated kar yotype. It follows a linear evolution from the CLL clone throughout the recurrent acquisition of CDKN2A